MetaCyc Pathway: lacto-series glycosphingolipids biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Ceramide glucosyltransferase:
an N-acylsphingosine + UDP-α-D-glucose→a β-D-glucosyl-N-acylsphingosine + H+ + UDP (EC 2.4.1.80)
RR42_RS35290
a β-D-glucosyl-N-acylsphingosine + UDP-α-D-galactose→a lactosylceramide + H+ + UDP (EC 2.4.1.274)
No genes
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase:
a lactosylceramide + UDP-N-acetyl-α-D-glucosamine→a lactotriaosylceramide + H+ + UDP (EC 2.4.1.206)
No genes
Glucosaminylgalactosylglucosylceramide beta-galactosyltransferase:
a lactotriaosylceramide + UDP-α-D-galactose→a lactotetraosylceramide + H+ + UDP (EC 2.4.1.86)
No genes
Galactoside 2-alpha-L-fucosyltransferase:
a lactotetraosylceramide + GDP-β-L-fucose→a III2-α-fucosyllactotetraosylceramide + GDP + H+ (EC 2.4.1.69)
No genes
a lactotetraosylceramide + CMP-N-acetyl-β-neuraminate→a ganglioside 3'-isoLM1 + CMP + H+ (EC 2.4.3.9)
No genes
a ganglioside 3'-isoLM1 + CMP-N-acetyl-β-neuraminate→a ganglioside 3',6'-isoLD1 + CMP + H+ (EC 2.4.3.1)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information