MetaCyc Pathway: type IV lipoteichoic acid biosynthesis (S. pneumoniae) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


UDP-α-D-glucose + a 1,2-diacyl-sn-glycerol→a 1,2-diacyl-3-O-(α-D-glucopyranosyl)-sn-glycerol + H+ + UDP (EC 2.4.1.337)
No genes
UDP-2-acetamido-4-amino-2,4,6-trideoxy-α-D-galactose + di-trans,octa-cis-undecaprenyl phosphate→2-acetamido-4-amino-2,4,6-trideoxy-α-D-galactosyl-diphospho-ditrans,octacis-undecaprenol + UMP
RR42_RS15730
D-alanine + ATP + a holo [D-alanyl carrier protein]→a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate (EC 6.2.1.54)
No genes
choline[out] + H+[out]→choline[in] + H+[in]
No genes
Choline kinase:
choline + ATP→phosphocholine + ADP + H+
(EC 2.7.1.32)
No genes
a D-alanyl-[D-alanyl carrier protein] + a phosphatidylglycerol[membrane]→2-O-D-alanyl-1-O-phosphatidylglycerol[out] + a holo [D-alanyl carrier protein][in] (EC 2.3.2.M5)
No genes
UDP-α-D-glucose + 2-acetamido-4-amino-2,4,6-trideoxy-α-D-galactosyl-diphospho-ditrans,octacis-undecaprenol→Glc-AATGal-PP-undecaprenol + H+ + UDP
No genes
Choline-phosphate cytidylyltransferase:
phosphocholine + CTP + H+→CDP-choline + diphosphate
(EC 2.7.7.15)
No genes
Glc-AATGal-PP-undecaprenol + CDP-ribitol→(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + CMP + H+
No genes
(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + UDP-N-acetyl-α-D-galactosamine→GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + H+ + UDP
No genes
GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + UDP-N-acetyl-α-D-galactosamine→GalNAc-GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + H+ + UDP
No genes
CDP-choline + GalNAc-GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol→(Chol-P-GalNAc)-GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + CMP + H+
No genes
CDP-choline + (Chol-P-GalNAc)-GalNAc-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol→(Chol-P-GalNAc)-(Chol-P-GalNAc)-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol + CMP + H+
No genes
n (Chol-P-GalNAc)-(Chol-P-GalNAc)-(Rib-ol)-P-Glc-AATGal-PP-undecaprenol→[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol + n-1 H+ + n-1 di-trans,octa-cis-undecaprenyl diphosphate
No genes
[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol + n UDP-N-acetyl-α-D-galactosamine→[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(GalNAc-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol + n H+ + n UDP
No genes
[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(GalNAc-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol[in]→[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(GalNAc-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol[out]
No genes
n 2-O-D-alanyl-1-O-phosphatidylglycerol + [(Chol-P-GalNAc)-(Chol-P-GalNAc)-(GalNAc-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol→[(Chol-P-GalNAc)-(Chol-P-GalNAc)-(D-Ala-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol + n a phosphatidylglycerol (EC 2.3.1.M32)
No genes
a 1,2-diacyl-3-O-(α-D-glucopyranosyl)-sn-glycerol + [(Chol-P-GalNAc)-(Chol-P-GalNAc)-(D-Ala-Rib-ol)-P-Glc-AATGal]n-PP-undecaprenol→type IV lipoteichoic acid + H+ + di-trans,octa-cis-undecaprenyl diphosphate (EC 2.7.8.M1)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information