MetaCyc Pathway: methyl tert-butyl ether degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


methyl tert-butyl ether + NADH + dioxygen + H+→tert-butoxymethanol + NAD+ + H2O (EC 1.14.13.M36)
RR42_RS09290
RR42_RS20735
tert-butoxymethanol + NAD+→tert-butyl formate + NADH + H+ (EC 1.1.1.M26)
No genes
tert-butyl formate + H2O→tert-butyl alcohol + formate + H+
No genes
tert-butyl alcohol + NADPH + dioxygen + H+→2-methylpropane-1,2-diol + NADP+ + H2O (EC 1.14.13.229)
No genes
2-methylpropane-1,2-diol + NAD+→2-hydroxy-2-methylpropanal + NADH + H+ (EC 1.1.1.400)
No genes
2-hydroxy-2-methylpropanal + NAD+ + H2O→2-hydroxy-2-methylpropanoate + NADH + 2 H+ (EC 1.2.1.98)
No genes
2-hydroxy-2-methylpropanoate + ATP + coenzyme A→2-hydroxy-2-methylpropanoyl-CoA + AMP + diphosphate (EC 6.2.1.M4)
No genes
2-hydroxy-2-methylpropanoyl-CoA→(S)-3-hydroxybutanoyl-CoA (EC 5.4.99.64)
No genes
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
RR42_RS01610
RR42_RS02510
RR42_RS03005
RR42_RS03440
RR42_RS05760
RR42_RS10265
RR42_RS11095
RR42_RS22630
RR42_RS24305
RR42_RS25375
RR42_RS28325
RR42_RS29465
RR42_RS31050
RR42_RS35270
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
RR42_RS00885
RR42_RS02515
RR42_RS03010
RR42_RS07610
RR42_RS07645
RR42_RS10260
RR42_RS10540
RR42_RS11085
RR42_RS16595
RR42_RS22625
RR42_RS24300
RR42_RS24970
RR42_RS25210
RR42_RS25380
RR42_RS25455
RR42_RS26090
RR42_RS27160
RR42_RS27235
RR42_RS28055
RR42_RS28390
RR42_RS31890
RR42_RS31920
RR42_RS35915
RR42_RS36320
RR42_RS37020

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information