MetaCyc Pathway: diphenyl ethers degradation in Cupriavidus basilensis FW507-4G11

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Biphenyl 2,3-dioxygenase:
diphenyl ether + NADPH + dioxygen + H+→(1S,2S)-3-phenoxycyclohexa-3,5-diene-1,2-diol + NADP+ (EC 1.14.12.18)
No genes
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase:
(1S,2S)-3-phenoxycyclohexa-3,5-diene-1,2-diol + NAD+→diphenyl ether 2,3-diol + NADH + H+ (EC 1.3.1.56)
No genes
Biphenyl-2,3-diol 1,2-dioxygenase:
diphenyl ether 2,3-diol + dioxygen→(2Z,4E)-2-hydroxy-6-oxo-6-phenoxyhexa-2,4-dienoate + H+ (EC 1.13.11.39)
RR42_RS05145
RR42_RS31960
(2Z,4E)-2-hydroxy-6-oxo-6-phenoxyhexa-2,4-dienoate→2-pyrone-6-carboxylate + phenol (spontaneous)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information