MetaCyc Pathway: CMP-diacetamido-8-epilegionaminic acid biosynthesis in Cupriavidus basilensis FW507-4G11

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UDP-N-acetylglucosamine 4,6-dehydratase (inverting):
UDP-N-acetyl-α-D-glucosamine→UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + H2O
(EC 4.2.1.115)
RR42_RS15810
UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase (in reverse):
UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + L-glutamate→UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-idosamine + 2-oxoglutarate
(EC 2.6.1.34)
No genes
UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-idosamine + acetyl-CoA→UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-idopyranose + coenzyme A + H+
No genes
UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-idopyranose→UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose
No genes
UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose + H2O→2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose + H+ + UDP
No genes
2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose + phosphoenolpyruvate + H2O→5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate + phosphate
No genes
5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate + CTP→CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate + diphosphate
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information