| (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + malonyl-CoA + H+→(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + NAD(P)H + H+→(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA + NAD(P)+ (EC 1.1.1.330) |
| No genes |
| (3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA→(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + a reduced two electron carrier→(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + an oxidized electron carrier (EC 1.3.1.93) |
| No genes |
| (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA→(2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| No genes |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA (EC 4.2.1.17) |
| RR42_RS00730 |
| RR42_RS02510 |
| RR42_RS02525 |
| RR42_RS03015 |
| RR42_RS04550 |
| RR42_RS05755 |
| RR42_RS05760 |
| RR42_RS07510 |
| RR42_RS10250 |
| RR42_RS10265 |
| RR42_RS10270 |
| RR42_RS11095 |
| RR42_RS12500 |
| RR42_RS12795 |
| RR42_RS13545 |
| RR42_RS16175 |
| RR42_RS16790 |
| RR42_RS18250 |
| RR42_RS18255 |
| RR42_RS19805 |
| RR42_RS19815 |
| RR42_RS22630 |
| RR42_RS22680 |
| RR42_RS23295 |
| RR42_RS23450 |
| RR42_RS23710 |
| RR42_RS24355 |
| RR42_RS24895 |
| RR42_RS25480 |
| RR42_RS25525 |
| RR42_RS25900 |
| RR42_RS28050 |
| RR42_RS28325 |
| RR42_RS28330 |
| RR42_RS28425 |
| RR42_RS28545 |
| RR42_RS28550 |
| RR42_RS29425 |
| RR42_RS29465 |
| RR42_RS29940 |
| RR42_RS29945 |
| RR42_RS31580 |
| RR42_RS31675 |
| RR42_RS31935 |
| RR42_RS31945 |
| RR42_RS34175 |
| RR42_RS34180 |
| RR42_RS34905 |
| RR42_RS35130 |
| RR42_RS35270 |
| RR42_RS36335 |
| RR42_RS36495 |
| (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| RR42_RS00885 |
| RR42_RS02515 |
| RR42_RS03010 |
| RR42_RS07610 |
| RR42_RS07645 |
| RR42_RS10260 |
| RR42_RS10540 |
| RR42_RS11085 |
| RR42_RS16595 |
| RR42_RS22625 |
| RR42_RS24300 |
| RR42_RS24970 |
| RR42_RS25210 |
| RR42_RS25380 |
| RR42_RS25455 |
| RR42_RS26090 |
| RR42_RS27160 |
| RR42_RS28055 |
| RR42_RS31890 |
| RR42_RS31920 |
| RR42_RS35915 |
| RR42_RS36320 |
| RR42_RS37020 |
| (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + a glycerolipid→a [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + coenzyme A |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information