MetaCyc Pathway: 2,3-dihydroxybenzoate degradation in Cupriavidus basilensis FW507-4G11

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2,3-dihydroxybenzoate 3,4-dioxygenase:
2,3-dihydroxybenzoate + dioxygen→3-carboxy-2-hydroxymuconate semialdehyde + H+ (EC 1.13.11.14)
No genes
3-carboxy-2-hydroxymuconate semialdehyde + H+→(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO2
No genes
(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + NAD+ + H2O→(2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+ (EC 1.2.1.85)
No genes
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate→(3E)-2-oxohex-3-enedioate (EC 5.3.2.6)
RR42_RS11545
RR42_RS32635
4-oxalocrotonate decarboxylase:
(3E)-2-oxohex-3-enedioate + H+→(2Z)-2-hydroxypenta-2,4-dienoate + CO2 (EC 4.1.1.77)
RR42_RS05105
RR42_RS31850
RR42_RS32640
RR42_RS32645

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information