MetaCyc Pathway: gentisate degradation II in Cupriavidus basilensis FW507-4G11

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Gentisate 1,2-dioxygenase:
gentisate + dioxygen→3-maleylpyruvate + H+
(EC 1.13.11.4)
RR42_RS24045
RR42_RS24165
RR42_RS24220
RR42_RS24280
RR42_RS30520
3-maleylpyruvate + H2O→maleate + pyruvate + H+ (EC 3.7.1.23)
RR42_RS24170
Maleate hydratase (in reverse):
maleate + H2O→(R)-malate
(EC 4.2.1.31)
RR42_RS14390
RR42_RS24180
D-malate dehydrogenase (decarboxylating):
(R)-malate + NAD+→pyruvate + CO2 + NADH
(EC 1.1.1.83)
RR42_RS02600
RR42_RS33755

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information