MetaCyc Pathway: L-arginine biosynthesis IV (archaea) in Cupriavidus basilensis FW507-4G11

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Carbamoyl-phosphate synthase (glutamine-hydrolyzing):
hydrogen carbonate + 2 ATP + L-glutamine + H2O→carbamoyl phosphate + L-glutamate + 2 ADP + 2 H+ + phosphate (EC 6.3.5.5)
RR42_RS13510
RR42_RS13520
L-glutamate + ATP + an [amino-group carrier protein]-C-terminal-L-glutamate→an [amino-group carrier protein]-C-terminal-γ-(L-glutamyl)-L-glutamate + ADP + H+ + phosphate (EC 6.3.2.60)
No genes
an [amino-group carrier protein]-C-terminal-γ-(L-glutamyl)-L-glutamate + ATP→an [amino-group carrier protein]-C-terminal-γ-(5-phospho-L-glutamyl)-L-glutamate + ADP (EC 2.7.2.19)
No genes
an [amino-group carrier protein]-C-terminal-γ-(5-phospho-L-glutamyl)-L-glutamate + NADPH + H+→an [amino-group carrier protein]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate + NADP+ + phosphate (EC 1.2.1.106)
No genes
L-glutamate + an [amino-group carrier protein]-C-terminal-γ-(L-glutamate 5-semialdehyde-2-yl)-L-glutamate→an [amino-group carrier protein]-C-terminal-γ-(L-ornithyl)-L-glutamate + 2-oxoglutarate (EC 2.6.1.124)
No genes
an [amino-group carrier protein]-C-terminal-γ-(L-ornithyl)-L-glutamate + H2O→L-ornithine + an [amino-group carrier protein]-C-terminal-L-glutamate (EC 3.5.1.132)
No genes
Ornithine carbamoyltransferase:
carbamoyl phosphate + L-ornithine→L-citrulline + H+ + phosphate (EC 2.1.3.3)
RR42_RS17175
Argininosuccinate synthase:
L-citrulline + ATP + L-aspartate→L-arginino-succinate + AMP + diphosphate + H+ (EC 6.3.4.5)
RR42_RS17170
Argininosuccinate lyase:
L-arginino-succinate→L-arginine + fumarate (EC 4.3.2.1)
RR42_RS15925

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information