MetaCyc Pathway: naringenin biosynthesis (engineered) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Tyrosine ammonia-lyase:
L-tyrosine→4-coumarate + ammonium
(EC 4.3.1.23; 4.3.1.25; 5.4.3.6)
RR42_RS01710
4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate
(EC 6.2.1.12)
RR42_RS36410
Naringenin-chalcone synthase:
(E)-4-coumaroyl-CoA + 3 malonyl-CoA + 3 H+→naringenin chalcone + 3 CO2 + 4 coenzyme A
(EC 2.3.1.74)
No genes
Chalcone isomerase:
naringenin chalcone→(2S)-naringenin
(EC 5.5.1.6)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information