MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
RR42_RS20530
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
RR42_RS03210
RR42_RS19870
RR42_RS33735
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
RR42_RS20530
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
RR42_RS12545
RR42_RS28540
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
RR42_RS02230
RR42_RS14465
RR42_RS29130
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
RR42_RS12035
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
RR42_RS01570
RR42_RS01590
RR42_RS02275
RR42_RS04985
RR42_RS05770
RR42_RS09190
RR42_RS09965
RR42_RS10785
RR42_RS12545
RR42_RS14560
RR42_RS15580
RR42_RS16470
RR42_RS21340
RR42_RS25980
RR42_RS26005
RR42_RS26015
RR42_RS26185
RR42_RS26625
RR42_RS28185
RR42_RS32165
RR42_RS33140
RR42_RS33805
RR42_RS35305
RR42_RS36780
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
RR42_RS02195
RR42_RS13905
RR42_RS27740
RR42_RS33090
RR42_RS37365
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
RR42_RS07365
RR42_RS07370
RR42_RS07380
RR42_RS10660
RR42_RS21775
RR42_RS24415
RR42_RS26120
RR42_RS26125
RR42_RS32980
RR42_RS33045
RR42_RS34220
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
RR42_RS01600
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
RR42_RS03095
RR42_RS03100
RR42_RS31375
RR42_RS31380
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
RR42_RS01335
RR42_RS06360
RR42_RS14345

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information