MetaCyc Pathway: wybutosine biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


guanine37 in tRNAPhe + S-adenosyl-L-methionine→an N1-methylguanine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.228)
RR42_RS04630
an N1-methylguanine37 in tRNAPhe + pyruvate + S-adenosyl-L-methionine→4-demethylwyosine37 in tRNAPhe + CO2 + 5'-deoxyadenosine + L-methionine + H2O (EC 4.1.3.44)
No genes
4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine→7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe + S-methyl-5'-thioadenosine + H+ (EC 2.5.1.114)
No genes
7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe + S-adenosyl-L-methionine→7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.282)
No genes
7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-methionine→7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + S-adenosyl-L-homocysteine (EC 2.1.1.290)
No genes
7-[(3S)-4-methoxy-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe + CO2 + S-adenosyl-L-methionine→wybutosine37 in tRNAPhe + S-adenosyl-L-homocysteine + 2 H+ (EC 2.3.1.231)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information