MetaCyc Pathway: 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II in Cupriavidus basilensis FW507-4G11

Add experiment(s):


pyridoxine[out] + H+[out]→pyridoxine[in] + H+[in]
No genes
Pyridoxal kinase:
pyridoxine + ATP→pyridoxine 5'-phosphate + ADP + H+ (EC 2.7.1.35)
No genes
Pyridoxine 4-dehydrogenase:
pyridoxine + NADP+→pyridoxal + NADPH + H+ (EC 1.1.1.65)
RR42_RS33100
Pyridoxal 5'-phosphate synthase:
pyridoxine 5'-phosphate + dioxygen→pyridoxal 5'-phosphate + hydrogen peroxide (EC 1.4.3.5)
RR42_RS06305
RR42_RS15320
Pyridoxal kinase:
pyridoxal + ATP→pyridoxal 5'-phosphate + ADP + H+ (EC 2.7.1.35)
No genes
pyridoxal 5'-phosphate + an [HMP-P synthase]-L-lysine→an [HMP-P synthase]-(PLP-imine)-L-lysine + H+ + H2O
No genes
an [HMP-P synthase]-(PLP-imine)-L-lysine + 2 Fe3+ + [an HMP-P synthase]-L-histidine + 4 H2O→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe2+ + 3-oxopropanoate + 2 H+ + an [HMP-P synthase]-3-(2-hydroxyacetyl)-L-alanine + an [HMP-P synthase]-L-lysine
No genes
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
RR42_RS01370

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information