MetaCyc Pathway: superpathway of adenosine nucleotides de novo biosynthesis I in Cupriavidus basilensis FW507-4G11

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Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylosuccinate + GDP + 2 H+ + phosphate
(EC 6.3.4.4)
RR42_RS13090
Adenylosuccinate lyase:
adenylosuccinate→AMP + fumarate
(EC 4.3.2.2)
RR42_RS17455
Adenylate kinase:
AMP + ATP→2 ADP
(EC 2.7.4.3)
RR42_RS03445
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O
(EC 1.17.4.1)
RR42_RS13290
RR42_RS17855
RR42_RS17860
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP
(EC 2.7.4.6)
RR42_RS13160

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information