MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleoside salvage in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium
(EC 3.5.4.5)
No genes
Deoxycytidine kinase:
2'-deoxycytidine + a nucleoside triphosphate→dCMP + a nucleoside diphosphate + H+
(EC 2.7.1.74)
No genes
Deoxynucleoside kinase:
2'-deoxyuridine + ATP→dUMP + ADP + H+
(EC 2.7.1.145; 2.7.1.21)
No genes
(Deoxy)nucleoside-phosphate kinase:
dCMP + ATP→dCDP + ADP
(EC 2.7.4.13; 2.7.4.14; 2.7.4.25)
RR42_RS04485
Thymidylate synthase:
dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate
(EC 2.1.1.45)
RR42_RS14740
Nucleoside-diphosphate kinase:
dCDP + ATP→dCTP + ADP
(EC 2.7.4.6)
RR42_RS03445
RR42_RS13160
Deoxynucleoside kinase:
thymidine + ATP→dTMP + ADP + H+
(EC 2.7.1.145; 2.7.1.21)
No genes
T(2)-induced deoxynucleotide kinase:
dTMP + ATP→dTDP + ADP
(EC 2.7.4.12; 2.7.4.13; 2.7.4.9)
RR42_RS04195
RR42_RS10905
Nucleoside-diphosphate kinase:
dTDP + ATP→dTTP + ADP
(EC 2.7.4.6)
RR42_RS03445
RR42_RS13160

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information