MetaCyc Pathway: 4-hydroxy-2-nonenal detoxification in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Glutathione transferase:
4-hydroxy-2-nonenal + glutathione→(glutathion-S-yl)-4-hydroxy-2-nonenal (EC 2.5.1.18)
RR42_RS00340
RR42_RS00915
RR42_RS01010
RR42_RS01415
RR42_RS01970
RR42_RS03605
RR42_RS05710
RR42_RS05765
RR42_RS11040
RR42_RS12325
RR42_RS15600
RR42_RS17460
RR42_RS20670
RR42_RS23260
RR42_RS30510
RR42_RS33460
RR42_RS34085
RR42_RS34590
RR42_RS37430
(glutathion-S-yl)-4-hydroxy-2-nonenal + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + L-glutamate (EC 3.4.19.13)
No genes
S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteine + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
S-(4-hydroxy-nonenal-3-yl)-L-cysteine + acetyl-CoA→4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ (EC 2.3.1.80)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information