MetaCyc Pathway: 2,2'-dihydroxybiphenyl degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


2-hydroxybiphenyl 3-monooxygenase:
2,2'-dihydroxybiphenyl + NADH + dioxygen + H+→2,2',3-trihydroxybiphenyl + NAD+ + H2O
(EC 1.14.13.44)
No genes
2,2',3-trihydroxybiphenyl + dioxygen→(2Z,2E)-2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H+
No genes
2,2',3-trihydroxybiphenyl + NADH + dioxygen + H+→2,2',3,3'-tetrahydroxybiphenyl + NAD+ + H2O
No genes
2,6-dioxo-6-phenylhexa-3-enoate hydrolase:
(2Z,2E)-2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate + H2O→salicylate + (2Z)-2-hydroxypenta-2,4-dienoate + H+
(EC 3.7.1.8)
No genes
2,2',3,3'-tetrahydroxybiphenyl + dioxygen→(2Z,2E)-2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H+
No genes
2,6-dioxo-6-phenylhexa-3-enoate hydrolase:
(2Z,2E)-2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + 2,3-dihydroxybenzoate + H+
(EC 3.7.1.8)
No genes
2,3-dihydroxybenzoate + NADH + dioxygen + 2 H+→pyrogallol + CO2 + NAD+ + H2O
No genes
Pyrogallol 1,2-oxygenase:
pyrogallol + dioxygen→(2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H+
(EC 1.13.11.35)
No genes
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate→(3E)-2-oxohex-3-enedioate (EC 5.3.2.6)
RR42_RS11545
RR42_RS32635
4-oxalocrotonate decarboxylase:
(3E)-2-oxohex-3-enedioate + H+→(2Z)-2-hydroxypenta-2,4-dienoate + CO2
(EC 4.1.1.77)
RR42_RS05105
RR42_RS31850
RR42_RS32640
RR42_RS32645

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information