MetaCyc Pathway: alginate degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Poly(alpha-L-guluronate) lyase:
alginate→n 4-deoxy-α-L-erythro-hex-4-enopyranuronate-α-L-guluronate (EC 4.2.2.11)
No genes
Poly(beta-D-mannuronate) lyase:
alginate→n 4-deoxy-α-L-erythro-hex-4-enopyranuronate-β-D-mannuronate (EC 4.2.2.3)
No genes
4-deoxy-α-L-erythro-hex-4-enopyranuronate-α-L-guluronate→2 4-deoxy-L-erythro-hex-4-enopyranuronate (EC 4.2.2.26)
No genes
4-deoxy-α-L-erythro-hex-4-enopyranuronate-β-D-mannuronate→2 4-deoxy-L-erythro-hex-4-enopyranuronate (EC 4.2.2.26)
No genes
4-deoxy-L-erythro-hex-4-enopyranuronate→(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate (EC 4.2.99.25)
No genes
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase (in reverse):
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+→2-dehydro-3-deoxy-D-gluconate + NADP+ (EC 1.1.1.126)
No genes
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
RR42_RS09470
RR42_RS28860

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information