MetaCyc Pathway: umbelliferone biosynthesis in Cupriavidus basilensis FW507-4G11

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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate
(EC 6.2.1.12)
RR42_RS36410
(E)-4-coumaroyl-CoA + 2-oxoglutarate + dioxygen→2,4-dihydroxycinnamoyl-CoA + CO2 + succinate (EC 1.14.11.62)
No genes
2,4-dihydroxycinnamoyl-CoA→umbelliferone + coenzyme A (spontaneous)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information