Naphthalene 1,2-dioxygenase:
naphthalene + NADH + dioxygen + H+→(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+ (EC 1.14.12.12) |
| No genes |
Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase:
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+→naphthalene-1,2-diol + NADH + H+ (EC 1.3.1.29) |
| No genes |
| naphthalene-1,2-diol + dioxygen→2-hydroxychromene-2-carboxylate + H+ (EC 1.13.11.56) |
| No genes |
| 2-hydroxychromene-2-carboxylate→trans-O-hydroxybenzylidenepyruvate (EC 5.99.1.4) |
| No genes |
| trans-O-hydroxybenzylidenepyruvate + H2O→salicylaldehyde + pyruvate (EC 4.1.2.45) |
| No genes |
Salicylaldehyde dehydrogenase:
salicylaldehyde + NAD+ + H2O→salicylate + NADH + 2 H+ (EC 1.2.1.65) |
| No genes |
Salicylate 1-monooxygenase:
salicylate + NADH + dioxygen + 2 H+→catechol + CO2 + NAD+ + H2O (EC 1.14.13.1) |
| RR42_RS03265 |
| RR42_RS06410 |
| RR42_RS14855 |
| RR42_RS21625 |
| RR42_RS22480 |
| RR42_RS24050 |
| RR42_RS24155 |
| RR42_RS24285 |
| RR42_RS25760 |
| RR42_RS30505 |
Catechol 2,3-dioxygenase:
catechol + dioxygen→(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H+ (EC 1.13.11.2) |
| RR42_RS32655 |
| RR42_RS34600 |
2-hydroxymuconate-semialdehyde hydrolase:
(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + formate + H+ (EC 3.7.1.9) |
| RR42_RS25595 |
| RR42_RS34060 |
2-oxopent-4-enoate hydratase (in reverse):
(2Z)-2-hydroxypenta-2,4-dienoate + H2O→(S)-4-hydroxy-2-oxopentanoate (EC 4.2.1.80) |
| RR42_RS05105 |
| RR42_RS27885 |
| RR42_RS32645 |
| RR42_RS34355 |
4-hydroxy-2-oxovalerate aldolase:
(S)-4-hydroxy-2-oxopentanoate→acetaldehyde + pyruvate (EC 4.1.3.39) |
| RR42_RS05095 |
| RR42_RS27900 |
| RR42_RS31860 |
| RR42_RS32625 |
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) |
| RR42_RS05100 |
| RR42_RS27895 |
| RR42_RS31855 |
| RR42_RS32630 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information