MetaCyc Pathway: testosterone and androsterone degradation to androstendione (aerobic) in Cupriavidus basilensis FW507-4G11

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3(or 17)-alpha-hydroxysteroid dehydrogenase:
androsterone + NAD(P)+→5α-androstanedione + NAD(P)H + H+ (EC 1.1.1.209; 1.1.1.213; 1.1.1.357; 1.1.1.50)
No genes
3(or 17)-beta-hydroxysteroid dehydrogenase:
testosterone + NAD(P)+→androstenedione + NAD(P)H + H+ (EC 1.1.1.51)
RR42_RS31985
3-oxo-5-alpha-steroid 4-dehydrogenase:
5α-androstanedione + an oxidized electron carrier→androstenedione + a reduced two electron carrier (EC 1.3.99.5)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information