MetaCyc Pathway: 6-gingerol analog biosynthesis (engineered) in Cupriavidus basilensis FW507-4G11

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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate
(EC 6.2.1.12)
RR42_RS36410
Butyrate--CoA ligase:
octanoate + ATP + coenzyme A→octanoyl-CoA + AMP + diphosphate
(EC 6.2.1.2; 6.2.1.3)
RR42_RS01625
RR42_RS18150
RR42_RS18540
RR42_RS25195
RR42_RS26915
RR42_RS28980
RR42_RS29035
RR42_RS29460
RR42_RS29475
RR42_RS36095
RR42_RS36385
RR42_RS36505
Acyl-CoA oxidase:
octanoyl-CoA + dioxygen→(2E)-oct-2-enoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
No genes
(2E)-oct-2-enoyl-CoA + H2O→(R)-3-hydroxyoctanoyl-CoA (EC 4.2.1.119)
No genes
(R)-3-hydroxyoctanoyl-CoA + NAD+→3-oxooctanoyl-CoA + NADH + H+ (EC 1.1.1.M19)
RR42_RS02510
RR42_RS05760
RR42_RS10265
RR42_RS11095
RR42_RS22630
RR42_RS28325
RR42_RS29465
RR42_RS31050
RR42_RS35270
3-oxooctanoyl-CoA + (E)-4-coumaroyl-CoA + H2O→1-(4-hydroxyphenyl)-1-decene-3,5-dione + CO2 + 2 coenzyme A
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information