MetaCyc Pathway: dehydrophos biosynthesis in Cupriavidus basilensis FW507-4G11

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Phosphoenolpyruvate mutase:
phosphoenolpyruvate + H+→3-phosphonopyruvate (EC 5.4.2.9)
RR42_RS22445
Phosphonopyruvate decarboxylase:
3-phosphonopyruvate + H+→phosphonoacetaldehyde + CO2 (EC 4.1.1.82)
RR42_RS22450
phosphonoacetaldehyde + NADH + H+→2-hydroxyethylphosphonate + NAD+ (EC 1.1.1.309)
No genes
2-hydroxyethylphosphonate + 2-oxoglutarate + dioxygen→1,2-dihydroxyethylphosphonate + CO2 + succinate
No genes
1,2-dihydroxyethylphosphonate + ATP→1-hydroxy-2-phosphorylethylphosphonate + ADP + H+
No genes
1-hydroxy-2-phosphorylethylphosphonate + NAD+→1-oxo-2-phosphorylethylphosphonate + NADH + 2 H+
No genes
1-oxo-2-phosphorylethylphosphonate + L-glutamate→1-amino-2-phosphorylethylphosphonate + 2-oxoglutarate
No genes
1-amino-2-phosphorylethylphosphonate + H+ + H2O→hydrogen acetylphosphonate + ammonium + phosphate
No genes
hydrogen acetylphosphonate + L-alanine→[(S)-1-aminoethyl]phosphonate + H+ + pyruvate
No genes
[(S)-1-aminoethyl]phosphonate + an L-leucyl-[tRNALeu]→hydrogen (1S)-1-[(2S)-2-amino-4-methylpentanamido]ethylphosphonate + a tRNALeu
No genes
hydrogen (1S)-1-[(2S)-2-amino-4-methylpentanamido]ethylphosphonate + S-adenosyl-L-methionine→(1S)-1-[(2S)-2-amino-4-methylpentanamido]ethyl(methoxy)phosphinate + S-adenosyl-L-homocysteine (EC 2.1.1.M5)
No genes
(1S)-1-[(2S)-2-amino-4-methylpentanamido]ethyl(methoxy)phosphinate + 2-oxoglutarate + dioxygen→1-[(2S)-2-amino-4-methylpentanamido]ethenyl(methoxy)phosphinate + CO2 + succinate + H2O
No genes
1-[(2S)-2-amino-4-methylpentanamido]ethenyl(methoxy)phosphinate + a glycyl-[tRNAGly]→dehydrophos + a tRNAGly + 2 H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information