MetaCyc Pathway: cis-geranyl-CoA degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Geranoyl-CoA carboxylase:
cis-geranyl-CoA + ATP + hydrogen carbonate→3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA + ADP + H+ + phosphate (EC 6.4.1.5)
RR42_RS29410
RR42_RS29420
RR42_RS32735
RR42_RS32750
Isohexenylglutaconyl-CoA hydratase (in reverse):
3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA + H2O→3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA (EC 4.2.1.57)
RR42_RS32740
3-hydroxy-3-isohexenylglutaryl-CoA lyase:
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA→acetate + 7-methyl-3-oxooct-6-enoyl-CoA (EC 4.1.3.26)
RR42_RS00955
Acetate--CoA ligase:
acetate + ATP + coenzyme A→acetyl-CoA + AMP + diphosphate (EC 6.2.1.1)
RR42_RS06210
RR42_RS10650
RR42_RS13880
RR42_RS22715
RR42_RS24890
RR42_RS29035
7-methyl-3-oxooct-6-enoyl-CoA + coenzyme A→acetyl-CoA + 5-methylhex-4-enoyl-CoA
No genes
5-methylhex-4-enoyl-CoA + an oxidized electron carrier→(2E)-5-methylhexa-2,4-dienoyl-CoA + a reduced two electron carrier
No genes
(2E)-5-methylhexa-2,4-dienoyl-CoA + H2O→3-hydroxy-5-methylhex-4-enoyl-CoA
No genes
3-hydroxy-5-methylhex-4-enoyl-CoA + an oxidized electron carrier→5-methyl-3-oxo-4-hexenoyl-CoA + a reduced two electron carrier
No genes
5-methyl-3-oxo-4-hexenoyl-CoA + coenzyme A→acetyl-CoA + 3-methylcrotonyl-CoA
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information