MetaCyc Pathway: pyruvate fermentation to acetone in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster
(EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
RR42_RS00885
RR42_RS02515
RR42_RS03010
RR42_RS07610
RR42_RS07645
RR42_RS10260
RR42_RS10540
RR42_RS11085
RR42_RS16595
RR42_RS22625
RR42_RS24300
RR42_RS24970
RR42_RS25210
RR42_RS25380
RR42_RS25455
RR42_RS26090
RR42_RS27160
RR42_RS27235
RR42_RS28055
RR42_RS28390
RR42_RS31890
RR42_RS31920
RR42_RS35915
RR42_RS36320
RR42_RS37020
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA
(EC 2.8.3.9)
No genes
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA
(EC 2.8.3.9)
RR42_RS10720
RR42_RS14835
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2
(EC 4.1.1.4)
RR42_RS01230

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information