MetaCyc Pathway: carbazole degradation in Cupriavidus basilensis FW507-4G11

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9H carbazole + NAD(P)H + dioxygen + H+→2'-aminobiphenyl-2,3-diol + NAD(P)+ (EC 1.14.12.22)
No genes
Biphenyl-2,3-diol 1,2-dioxygenase:
2'-aminobiphenyl-2,3-diol + dioxygen→(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H+
(EC 1.13.11.39)
RR42_RS05145
RR42_RS31960
(2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O→anthranilate + (2E)-2-hydroxypenta-2,4-dienoate + H+ (EC 3.7.1.13)
No genes
(2E)-2-hydroxypenta-2,4-dienoate→2-oxopent-4-enoate
No genes
2-oxopent-4-enoate→(2Z)-2-hydroxypenta-2,4-dienoate (spontaneous) (EC 5.3.2.M1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information