MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Cupriavidus basilensis FW507-4G11

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
RR42_RS00730
RR42_RS02510
RR42_RS02525
RR42_RS03015
RR42_RS04550
RR42_RS05755
RR42_RS05760
RR42_RS07510
RR42_RS10250
RR42_RS10265
RR42_RS10270
RR42_RS11095
RR42_RS12500
RR42_RS12795
RR42_RS13545
RR42_RS16175
RR42_RS16790
RR42_RS18250
RR42_RS18255
RR42_RS19805
RR42_RS19815
RR42_RS22630
RR42_RS22680
RR42_RS23295
RR42_RS23450
RR42_RS23710
RR42_RS24355
RR42_RS24895
RR42_RS25480
RR42_RS25525
RR42_RS25900
RR42_RS28050
RR42_RS28325
RR42_RS28330
RR42_RS28425
RR42_RS28545
RR42_RS28550
RR42_RS29425
RR42_RS29465
RR42_RS29940
RR42_RS29945
RR42_RS31580
RR42_RS31675
RR42_RS31935
RR42_RS31945
RR42_RS34175
RR42_RS34180
RR42_RS34905
RR42_RS35130
RR42_RS35270
RR42_RS36335
RR42_RS36495
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information