MetaCyc Pathway: thymine degradation in Cupriavidus basilensis FW507-4G11

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Dihydropyrimidine dehydrogenase (NADP(+)) (in reverse):
thymine + NADPH + H+→5,6-dihydrothymine + NADP+ (EC 1.3.1.2)
No genes
Dihydropyrimidinase:
5,6-dihydrothymine + H2O→3-(carbamoylamino)-2-methylpropanoate + H+ (EC 3.5.2.2)
RR42_RS00365
RR42_RS16440
Beta-ureidopropionase:
3-(carbamoylamino)-2-methylpropanoate + 2 H+ + H2O→(R)-3-amino-2-methylpropanoate + ammonium + CO2 (EC 3.5.1.6)
RR42_RS07955
RR42_RS09415
RR42_RS21390
RR42_RS26250

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information