MetaCyc Pathway: melatonin degradation I in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Unspecific monooxygenase:
melatonin + dioxygen + a reduced [NADPH-hemoprotein reductase]→6-hydroxymelatonin + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.1)
RR42_RS19955
Unspecific monooxygenase:
melatonin + dioxygen + a reduced [NADPH-hemoprotein reductase]→N-acetyl-serotonin + formaldehyde + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.1)
RR42_RS19955
Aryl sulfotransferase:
6-hydroxymelatonin + 3'-phosphoadenylyl-sulfate→6-sulfatoxymelatonin + adenosine 3',5'-bisphosphate + H+ (EC 2.8.2.1)
No genes
Aryl sulfotransferase:
N-acetyl-serotonin + 3'-phosphoadenylyl-sulfate→N-acetyl-serotonin sulfate + adenosine 3',5'-bisphosphate + H+ (EC 2.8.2.1)
No genes
Glucuronosyltransferase:
N-acetyl-serotonin + UDP-α-D-glucuronate→N-acetyl-serotonin glucuronide + H+ + UDP (EC 2.4.1.17)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information