MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
RR42_RS26695
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
RR42_RS24620
RR42_RS24630
RR42_RS24640
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
RR42_RS01275
RR42_RS04280
RR42_RS11360
RR42_RS13660
RR42_RS18500
RR42_RS21485
RR42_RS23750
RR42_RS24065
RR42_RS24390
RR42_RS24705
RR42_RS24840
RR42_RS25005
RR42_RS25010
RR42_RS26255
RR42_RS27350
RR42_RS27780
RR42_RS29955
RR42_RS32140
RR42_RS34255

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information