MetaCyc Pathway: 4-chlorobenzoate degradation in Cupriavidus basilensis FW507-4G11

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4-chlorobenzoate--CoA ligase:
4-chlorobenzoate + ATP + coenzyme A→4-chlorobenzoyl-coA + AMP + diphosphate
(EC 6.2.1.33)
No genes
4-chlorobenzoyl-CoA dehalogenase:
4-chlorobenzoyl-coA + H2O→4-hydroxybenzoyl-CoA + chloride + H+
(EC 3.8.1.7)
No genes
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+
(EC 3.1.2.23)
RR42_RS06545
RR42_RS13530
4-hydroxybenzoate 3-monooxygenase:
4-hydroxybenzoate + NADPH + dioxygen + H+→protocatechuate + NADP+ + H2O
(EC 1.14.13.2)
RR42_RS21940

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information