MetaCyc Pathway: 4-methylcatechol degradation (ortho cleavage) in Cupriavidus basilensis FW507-4G11

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4-methylcatechol + dioxygen→3-methyl-cis,cis-muconate + 2 H+
No genes
Chloromuconate cycloisomerase (in reverse):
3-methyl-cis,cis-muconate + H+→4-methylmuconolactone (EC 5.5.1.7)
No genes
4-carboxymethyl-4-methylbutenolide mutase:
4-methylmuconolactone→3-methylmuconolactone (EC 5.4.99.14)
RR42_RS10020
Muconolactone Delta-isomerase:
3-methylmuconolactone→4-methyl-3-oxoadipate-enol-lactone (EC 5.3.3.4)
RR42_RS10025
RR42_RS10695
RR42_RS21840
RR42_RS33065
3-oxoadipate enol-lactonase:
4-methyl-3-oxoadipate-enol-lactone + H2O→4-methyl-3-oxoadipate + H+ (EC 3.1.1.24)
RR42_RS00755
RR42_RS10565
RR42_RS10690
RR42_RS21850
RR42_RS24710
RR42_RS30700
RR42_RS32050
3-oxoadipate CoA-transferase:
4-methyl-3-oxoadipate + succinyl-CoA→4-methyl-3-oxoadipyl-CoA + succinate (EC 2.8.3.6)
RR42_RS10005
RR42_RS10010
RR42_RS22965
RR42_RS22970
RR42_RS31950
RR42_RS31955
RR42_RS35920
RR42_RS35925
3-oxoadipyl-CoA thiolase (in reverse):
4-methyl-3-oxoadipyl-CoA + coenzyme A→acetyl-CoA + (2S)-methylsuccinyl-CoA (EC 2.3.1.174)
RR42_RS35915

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information