MetaCyc Pathway: 2,4,6-trichlorophenol degradation in Cupriavidus basilensis FW507-4G11

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2,4,6-trichlorophenol + FADH2 + dioxygen→2,6-dichloro-1,4-benzoquinone + chloride + FAD + H+ + H2O (EC 1.14.14.173)
No genes
2,6-dichloro-1,4-benzoquinone + H2O→2-chloro-6-hydroxy-1,4-benzoquinone + chloride + H+ (EC 1.14.14.173)
No genes
2-chloro-6-hydroxy-1,4-benzoquinone + FADH2→2-chlorobenzene-1,4,6-triol + FAD + H+ (spontaneous)
No genes
2-chlorobenzene-1,4,6-triol + dioxygen→2-chloromaleylacetate + 2 H+
RR42_RS32880
Maleylacetate reductase (in reverse):
2-chloromaleylacetate + NAD(P)H + H+→5-chloro-3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
No genes
5-chloro-3-oxoadipate→2-maleylacetate + chloride + H+ (spontaneous)
No genes
Maleylacetate reductase (in reverse):
2-maleylacetate + NAD(P)H + H+→3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
RR42_RS32920
RR42_RS34620

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information