MetaCyc Pathway: 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I in Cupriavidus basilensis FW507-4G11

GTP cyclohydrolase I: GTP + H2O→7,8-dihydroneopterin 3'-triphosphate + formate + H+ (EC 3.5.4.16)

RR42_RS15000

RR42_RS34345

7,8-dihydroneopterin 3'-triphosphate + H2O→7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ (EC 3.6.1.67)

RR42_RS02470

7,8-dihydroneopterin 3'-phosphate + H2O→D-erythro-7,8-dihydroneopterin + phosphate

No genes

Dihydroneopterin aldolase: D-erythro-7,8-dihydroneopterin→6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde (EC 4.1.2.25)

RR42_RS01440

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase: 6-(hydroxymethyl)-7,8-dihydropterin + ATP→(7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ (EC 2.7.6.3)

RR42_RS17240

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information