MetaCyc Pathway: malonate degradation II (biotin-dependent) in Cupriavidus basilensis FW507-4G11

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ACP-SH:acetate ligase:
acetate + [a holo malonate decarboxylase acyl-carrier-protein] + ATP→an acetyl-[holo malonate decarboxylase acyl-carrier protein] + AMP + diphosphate
(EC 6.2.1.35)
No genes
Acetyl-S-ACP:malonate ACP transferase:
an acetyl-[holo malonate decarboxylase acyl-carrier protein] + malonate→acetate + a malonyl-[holo malonate decarboxylase acyl-carrier protein]
(EC 2.3.1.187)
RR42_RS02965
Malonyl-S-ACP:biotin-protein carboxyltransferase:
a malonyl-[holo malonate decarboxylase acyl-carrier protein] + [a biotinylated MadF protein]→an acetyl-[holo malonate decarboxylase acyl-carrier protein] + [a carboxylated biotinylated MadF protein]
(EC 2.1.3.10)
No genes
[a carboxylated biotinylated MadF protein][in] + n Na+[in] + H+[in]→[a biotinylated MadF protein][in] + CO2[in] + n Na+[out] (EC 7.2.4.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information