MetaCyc Pathway: chlorogenic acid biosynthesis II in Cupriavidus basilensis FW507-4G11

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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
RR42_RS36410
Shikimate O-hydroxycinnamoyltransferase:
(E)-4-coumaroyl-CoA + shikimate→trans-5-O-(4-coumaroyl)shikimate + coenzyme A (EC 2.3.1.133)
No genes
Shikimate O-hydroxycinnamoyltransferase:
(E)-4-coumaroyl-CoA + L-quinate→trans-5-O-(4-coumaroyl)-D-quinate + coenzyme A (EC 2.3.1.133)
No genes
trans-5-O-(4-coumaroyl)-D-quinate + dioxygen + a reduced [NADPH-hemoprotein reductase]→chlorogenate + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.96)
No genes
trans-5-O-(4-coumaroyl)shikimate + dioxygen + a reduced [NADPH-hemoprotein reductase]→5-O-caffeoylshikimate + an oxidized [NADPH-hemoprotein reductase] + H2O (EC 1.14.14.96)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information