MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Cupriavidus basilensis FW507-4G11

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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
RR42_RS15905
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
RR42_RS09325
RR42_RS10505
RR42_RS14430
RR42_RS32385
RR42_RS36245
oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)
No genes
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
RR42_RS11270
RR42_RS14490
RR42_RS23515
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
RR42_RS02195
RR42_RS13905
RR42_RS27740
RR42_RS33090
RR42_RS37365
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
RR42_RS11270
RR42_RS14490
RR42_RS23515
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)
RR42_RS14445
RR42_RS14455
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
RR42_RS17135
RR42_RS22955
RR42_RS28800
RR42_RS29535

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information