MetaCyc Pathway: superpathway of CDP-glucose-derived O-antigen building blocks biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Glucose-1-phosphate cytidylyltransferase:
α-D-glucopyranose 1-phosphate + CTP + H+→CDP-α-D-glucose + diphosphate (EC 2.7.7.33)
RR42_RS23610
CDP-glucose 4,6-dehydratase:
CDP-α-D-glucose→CDP-4-dehydro-6-deoxy-α-D-glucose + H2O (EC 4.2.1.45)
RR42_RS23605
CDP-4-dehydro-6-deoxyglucose reductase (in reverse):
CDP-4-dehydro-6-deoxy-α-D-glucose + NAD(P)H + H+→CDP-4-dehydro-3,6-dideoxy-α-D-glucose + NAD(P)+ + H2O (EC 1.17.1.1)
RR42_RS16950
RR42_RS27360
CDP-4-dehydro-3,6-dideoxy-α-D-glucose + NADPH + H+→CDP-α-abequose + NADP+ (EC 1.1.1.341)
No genes
CDP-4-dehydro-3,6-dideoxy-α-D-glucose + NADPH + H+→CDP-α-D-paratose + NADP+ (EC 1.1.1.342)
No genes
CDP-4-dehydro-3,6-dideoxy-α-D-glucose→CDP-3,6-dideoxy-D-glycero-4-hexulose (EC 5.1.3.M5)
No genes
CDP-paratose 2-epimerase:
CDP-α-D-paratose→CDP-α-D-tyvelose (EC 5.1.3.10)
No genes
CDP-3,6-dideoxy-D-glycero-4-hexulose + NAD(P)H + H+→CDP-ascarylose + NAD(P)+ (EC 1.1.1.M47)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information