MetaCyc Pathway: 4-hydroxybenzoate biosynthesis I (eukaryotes) in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
RR42_RS01570
RR42_RS01590
RR42_RS02275
RR42_RS04465
RR42_RS04985
RR42_RS05770
RR42_RS05990
RR42_RS09190
RR42_RS09965
RR42_RS10785
RR42_RS12545
RR42_RS14560
RR42_RS15580
RR42_RS16470
RR42_RS18910
RR42_RS21340
RR42_RS25980
RR42_RS26005
RR42_RS26015
RR42_RS26185
RR42_RS26625
RR42_RS28185
RR42_RS32165
RR42_RS33140
RR42_RS33490
RR42_RS33805
RR42_RS35305
RR42_RS36780
Indolelactate dehydrogenase (in reverse):
3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + H2O→4-hydroxybenzaldehyde + acetate
No genes
4-hydroxybenzaldehyde dehydrogenase:
4-hydroxybenzaldehyde + NAD+ + H2O→4-hydroxybenzoate + NADH + 2 H+ (EC 1.2.1.64)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information