MetaCyc Pathway: capsaicin biosynthesis in Cupriavidus basilensis FW507-4G11

Add experiment(s):


Caffeoyl-CoA O-methyltransferase:
(E)-caffeoyl-CoA + S-adenosyl-L-methionine→feruloyl-CoA + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.104)
No genes
isobutanoyl-CoA + 2 a malonyl-[acp] + 9 NADPH + 10 H+→(E)-8-methylnon-6-enoate + 2 a soluble [acyl-carrier protein] + coenzyme A + 9 NADP+ + 5 H2O
No genes
feruloyl-CoA + H2O→3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA (EC 4.1.2.61)
No genes
Long-chain-fatty-acid--CoA ligase:
(E)-8-methylnon-6-enoate + ATP + coenzyme A→(E)-8-methylnon-6-enoyl-CoA + ADP + phosphate (EC 6.2.1.3)
RR42_RS01625
RR42_RS18150
RR42_RS18540
RR42_RS25195
RR42_RS26915
RR42_RS28980
RR42_RS29035
RR42_RS29460
RR42_RS29475
RR42_RS36095
RR42_RS36385
RR42_RS36505
3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA→vanillin + acetyl-CoA (EC 4.1.2.61)
No genes
vanillin + L-alanine→vanillylamine + pyruvate (EC 2.6.1.119)
No genes
(E)-8-methylnon-6-enoyl-CoA + vanillylamine→capsaicin + coenzyme A + H+ (EC 2.3.2.35)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information