MetaCyc Pathway: succinate fermentation to butanoate in Cupriavidus basilensis FW507-4G11

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succinate + acetyl-CoA→succinyl-CoA + acetate (EC 2.8.3.18)
No genes
succinyl-CoA + NADPH + H+→succinate semialdehyde + coenzyme A + NADP+ (EC 1.2.1.76)
No genes
4-hydroxybutyrate dehydrogenase (in reverse):
succinate semialdehyde + NADH + H+→4-hydroxybutanoate + NAD+
(EC 1.1.1.61)
No genes
4-hydroxybutanoate + acetyl-CoA→4-hydroxybutanoyl-CoA + acetate (EC 2.8.3.M6)
No genes
4-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.120)
No genes
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
butanoyl-CoA + acetate→butanoate + acetyl-CoA
(EC 2.8.3.1; 2.8.3.8)
RR42_RS10720
RR42_RS14835

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information