MetaCyc Pathway: 4-chloronitrobenzene degradation in Cupriavidus basilensis FW507-4G11

Add experiment(s):


1-chloro-4-nitrobenzene + NADPH + H+→1-chloro-4-nitrosobenzene + NADP+ + H2O (EC 1.7.1.16)
No genes
1-chloro-4-nitrosobenzene + NADPH + H+→1-chloro-4-hydroxylaminobenzene + NADP+ (EC 1.7.1.16)
No genes
(Hydroxyamino)benzene mutase:
1-chloro-4-hydroxylaminobenzene→2-amino-5-chlorophenol
(EC 5.4.4.1)
No genes
2-amino-5-chlorophenol + dioxygen→(2Z,4Z)-2-amino-5-chloro-6-oxohexa-2,4-dienoate + H+ (EC 1.13.11.76)
No genes
Aminomuconate-semialdehyde dehydrogenase:
(2Z,4Z)-2-amino-5-chloro-6-oxohexa-2,4-dienoate + NAD+ + H2O→(2Z,4Z)-2-amino-5-chlorohexa-2,4-dienedioate + NADH + 2 H+
(EC 1.2.1.32)
RR42_RS05110
RR42_RS32650
(2Z,4Z)-2-amino-5-chlorohexa-2,4-dienedioate + H+ + H2O→(2Z,4Z)-2-chloro-5-hydroxyhexa-2,4-dienedioate + ammonium (EC 3.5.99.11)
No genes
(2Z,4Z)-2-chloro-5-hydroxyhexa-2,4-dienedioate→(3E)-2-chloro-5-oxohex-3-enedioate (EC 5.3.2.6)
RR42_RS32635
4-oxalocrotonate decarboxylase:
(3E)-2-chloro-5-oxohex-3-enedioate + H+→(3E)-5-chloro-2-oxopent-3-enoate + CO2
(EC 4.1.1.77)
RR42_RS05105
RR42_RS31850
RR42_RS32640
RR42_RS32645
2-oxopent-4-enoate hydratase (in reverse):
(3E)-5-chloro-2-oxopent-3-enoate + H2O→5-chloro-4-hydroxy-2-oxopentanoate
(EC 4.2.1.80)
RR42_RS05105
RR42_RS27885
RR42_RS32645
RR42_RS34355

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information