MetaCyc Pathway: vitamin B6 degradation I in Cupriavidus basilensis FW507-4G11

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Pyridoxamine--pyruvate transaminase:
pyridoxamine + pyruvate→pyridoxal + L-alanine (EC 2.6.1.30)
No genes
Pyridoxine 4-oxidase:
pyridoxine + dioxygen→pyridoxal + hydrogen peroxide (EC 1.1.3.12)
RR42_RS20290
Pyridoxal 4-dehydrogenase:
pyridoxal + NAD+→4-pyridoxolactone + NADH + H+ (EC 1.1.1.107)
No genes
4-pyridoxolactonase:
4-pyridoxolactone + H2O→4-pyridoxate + H+ (EC 3.1.1.27)
No genes
4-pyridoxate + an oxidized electron carrier→5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + a reduced two electron carrier (EC 1.1.99.42)
No genes
5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NAD+ + H2O→3-hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + 2 H+ (EC 1.2.1.100)
No genes
3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase:
3-hydroxy-2-methylpyridine-4,5-dicarboxylate + H+→3-hydroxy-2-methylpyridine-5-carboxylate + CO2 (EC 4.1.1.51)
No genes
3-hydroxy-2-methylpyridine-5-carboxylate + NAD(P)H + dioxygen→E-2-(acetamidomethylidene)succinate + NAD(P)+ (EC 1.14.13.242)
No genes
2-(acetamidomethylene)succinate hydrolase:
E-2-(acetamidomethylidene)succinate + H+ + 2 H2O→succinate semialdehyde + acetate + ammonium + CO2 (EC 3.5.1.29)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information