MetaCyc Pathway: methylglyoxal degradation VIII in Cupriavidus basilensis FW507-4G11

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Lactoylglutathione lyase (in reverse):
methylglyoxal + glutathione→(R)-S-lactoylglutathione
(EC 4.4.1.5)
RR42_RS02800
RR42_RS21780
RR42_RS29360
Hydroxyacylglutathione hydrolase:
(R)-S-lactoylglutathione + H2O→(R)-lactate + glutathione + H+
(EC 3.1.2.6)
RR42_RS13570
RR42_RS19750
RR42_RS20090
RR42_RS35440
D-lactate dehydrogenase (cytochrome):
(R)-lactate + 2 an oxidized c-type cytochrome→pyruvate + 2 a reduced c-type cytochrome + 2 H+
(EC 1.1.2.4)
RR42_RS17285

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information