MetaCyc Pathway: trans-4-hydroxy-L-proline degradation II in Cupriavidus basilensis FW507-4G11

Add experiment(s):


4-hydroxyproline epimerase:
trans-4-hydroxy-L-proline→(4R)-4-hydroxy-D-proline (EC 5.1.1.8)
RR42_RS36345
(4R)-4-hydroxy-D-proline + a reduced two electron carrier + dioxygen→1-pyrroline-4-hydroxy-2-carboxylate + an oxidized electron carrier + H+ + 2 H2O
RR42_RS36350
RR42_RS36360
1-pyrroline-4-hydroxy-2-carboxylate deaminase:
1-pyrroline-4-hydroxy-2-carboxylate + H+ + H2O→2,5-dioxopentanoate + ammonium (EC 3.5.4.22)
RR42_RS36370
2,5-dioxovalerate dehydrogenase:
2,5-dioxopentanoate + NADP+ + H2O→2-oxoglutarate + NADPH + 2 H+ (EC 1.2.1.26)
RR42_RS04830
RR42_RS23090
RR42_RS27350

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information