MetaCyc Pathway: 2-oxoglutarate decarboxylation to succinyl-CoA in Cupriavidus basilensis FW507-4G11

a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2-oxoglutarate + H+→a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine + CO2 (EC 1.2.1.105; 1.2.4.2)

RR42_RS12940

a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine + coenzyme A→a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + succinyl-CoA (EC 1.2.1.105; 2.3.1.61)

RR42_RS12935

a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + NAD+→a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + NADH + H+ (EC 1.2.1.105; 1.8.1.4)

RR42_RS07380

RR42_RS12930

RR42_RS21770

RR42_RS26115

RR42_RS34380

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information