MetaCyc Pathway: mevalonate degradation in Cupriavidus basilensis FW507-4G11

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Hydroxymethylglutaryl-CoA reductase:
(R)-mevalonate + coenzyme A + 2 NAD+→(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ (EC 1.1.1.88)
No genes
Hydroxymethylglutaryl-CoA lyase:
(S)-3-hydroxy-3-methylglutaryl-CoA→acetoacetate + acetyl-CoA (EC 4.1.3.4)
RR42_RS00955
RR42_RS12420
RR42_RS12425
RR42_RS13255
RR42_RS25095
RR42_RS25280
RR42_RS25285

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information