Nicotinate dehydrogenase:
nicotinate + NADP+ + H2O→6-hydroxynicotinate + NADPH + H+ (EC 1.17.1.5) |
| No genes |
6-hydroxynicotinate reductase (in reverse):
6-hydroxynicotinate + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→6-oxo-1,4,5,6-tetrahydronicotinate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.3.7.1) |
| No genes |
Enamidase:
6-oxo-1,4,5,6-tetrahydronicotinate + 2 H2O→(S)-2-formylglutarate + ammonium (EC 3.5.2.18) |
| No genes |
2-hydroxymethylglutarate dehydrogenase (in reverse):
(S)-2-formylglutarate + NADH + H+→(S)-2-hydroxymethylglutarate + NAD+ (EC 1.1.1.291) |
| No genes |
| (S)-2-hydroxymethylglutarate→2-methyleneglutarate + H2O |
| No genes |
2-methyleneglutarate mutase:
2-methyleneglutarate→(R)-3-methylitaconate (EC 5.4.99.4) |
| No genes |
Methylitaconate Delta-isomerase:
(R)-3-methylitaconate→dimethylmaleate (EC 5.3.3.6) |
| No genes |
Dimethylmaleate hydratase (in reverse):
dimethylmaleate + H2O→(2R,3S)-2,3-dimethylmalate (EC 4.2.1.85) |
| No genes |
2,3-dimethylmalate lyase:
(2R,3S)-2,3-dimethylmalate→pyruvate + propanoate (EC 4.1.3.32) |
| RR42_RS22765 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information