MetaCyc Pathway: glycine betaine degradation II (mammalian) in Cupriavidus basilensis FW507-4G11

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Betaine--homocysteine S-methyltransferase:
glycine betaine + L-homocysteine→N,N-dimethylglycine + L-methionine (EC 2.1.1.5)
No genes
N,N-dimethylglycine + an oxidized electron-transfer flavoprotein + H+ + a tetrahydrofolate→sarcosine + a reduced electron-transfer flavoprotein + a 5,10-methylenetetrahydrofolate (EC 1.5.8.4)
No genes
sarcosine + an oxidized electron-transfer flavoprotein + H+ + a tetrahydrofolate→glycine + a reduced electron-transfer flavoprotein + a 5,10-methylenetetrahydrofolate (EC 1.5.8.3)
No genes
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
RR42_RS15485

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information