MetaCyc Pathway: vitamin E biosynthesis (tocopherols) in Cupriavidus basilensis FW507-4G11

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4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
RR42_RS32440
RR42_RS32485
RR42_RS33500
homogentisate + phytyl diphosphate + H+→2-methyl-6-phytyl-1,4-benzoquinol + CO2 + diphosphate (EC 2.5.1.115)
No genes
2-methyl-6-phytyl-1,4-benzoquinol + S-adenosyl-L-methionine→2,3-dimethyl-6-phytyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.295)
No genes
2-methyl-6-phytyl-1,4-benzoquinol→δ-tocopherol (EC 5.5.1.24)
No genes
2,3-dimethyl-6-phytyl-1,4-benzoquinol→γ-tocopherol (EC 5.5.1.24)
No genes
Tocopherol O-methyltransferase:
δ-tocopherol + S-adenosyl-L-methionine→β-tocopherol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.95)
No genes
Tocopherol O-methyltransferase:
γ-tocopherol + S-adenosyl-L-methionine→α-tocopherol + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.95)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information